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Some brachyuran crabs from the Pliocene of a new outcrop nearby Borgomanero (Novara, Piedmont, NW Italy) are reported. This study allows us to recognize a peculiar brachyuran crabs assemblage including: Macropipus cf. M. tuberculatus Prestandrea, 1833 (Polybiidae Ortmann, 1893), first report for this species from the Pliocene fossil record, and an indeterminate representative of Mursia Leach in Desmarest, 1822 (Calappidae De Haan, 1833), genus never recorded previously in the Mediterranean basin. Finally, a single chela is referred to Calappa sp. (Calappidae De Haan, 1833).